Detalhe da pesquisa
1.
Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag.
Nat Methods
; 20(6): 898-907, 2023 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-37156841
2.
USP1 Is Required for Replication Fork Protection in BRCA1-Deficient Tumors.
Mol Cell
; 72(6): 925-941.e4, 2018 12 20.
Artigo
Inglês
| MEDLINE | ID: mdl-30576655
3.
Reducing the inherent auto-inhibitory interaction within the pegRNA enhances prime editing efficiency.
Nucleic Acids Res
; 51(13): 6966-6980, 2023 07 21.
Artigo
Inglês
| MEDLINE | ID: mdl-37246708
4.
Enhanced Cas12a editing in mammalian cells and zebrafish.
Nucleic Acids Res
; 47(8): 4169-4180, 2019 05 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30892626
5.
Addressing the dNTP bottleneck restricting prime editing activity.
bioRxiv
; 2023 Oct 29.
Artigo
Inglês
| MEDLINE | ID: mdl-37904991
6.
Optimization of Nuclear Localization Signal Composition Improves CRISPR-Cas12a Editing Rates in Human Primary Cells.
GEN Biotechnol
; 1(3): 271-284, 2022 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38405215
7.
Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice.
Nat Commun
; 12(1): 2121, 2021 04 09.
Artigo
Inglês
| MEDLINE | ID: mdl-33837189
8.
TRIP13 regulates DNA repair pathway choice through REV7 conformational change.
Nat Cell Biol
; 22(1): 87-96, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31915374